I know of one person that has PWS on her spine and head and that has had three children with PWS. The first two just have little spots on their body. But the last one had PWS with Sturge Weber Syndrome and has had severe seizures and has had a couple brain surgeries. So far there has not been any research to see if her and her genics have been linked to her children having PWS but it is possible.
Thought I would share.